What are the benefits of the high-pressure homogenization of nanoparticles?

The nanoparticle is of the highest interest to the scientific community. Though nanoparticle preparation can be done through multiple methods, high-pressure homogenization is most commonly used. However, there are good reasons behind it. The research on nanoparticles can lead to protein detection, gene delivery, drug delivery system, tissue engineering, fluorescent biological labels and more.

So, to know the benefits of high-pressure homogenization nanoparticles, read on.

    • Customised forces- In a high-pressure homogenizer, both mechanical force and pressure are used to get an even and consistent product. This is a bit different than other mixing equipment. Mechanical forces include cavitation, process intensity, turbulence, impact and shear. High-quality homogenizers allow technicians to adjust these forces so that the end results can be optimised.

    • Hot and cold options- High-pressure homogenization can be obtained by hot or cold options. In hot homogenization, heat is used above the lipid melting point, but it comes with a limitation in the drug delivery area. Hot homogenization results in drug loss from the aqueous phase, heightened product degradation, uncertain lipid transitions and more. However, cold homogenization was introduced to fight the hot homogenization’s limitations.

    • Smaller particles size- High-pressure homogenizers are unique in their own way because a significant amount of pressure is required alongside mechanical forces. These forces work together to give you smaller size particles, increasing nanoparticle surface area and bioavailability.
These are a few benefits of high-pressure homogenization nanoparticles. This is a preferred method over others because it has the power to reduce particle sizes drastically than other emulsification methods.

Nanoparticles production involves emulsification, which can be obtained by homogenization. The first step in achieving quality nanoparticles is having consistent particle size distribution, which is a key benefit for researchers and corporations.